Making the effect visible - OX40 targeting nanobodies for in vivo imaging of activated T cells
Desiree Isabella Frecot, Simone Blaess, Teresa R. Wagner, Philipp D. Kaiser, Bjoern Traenkle, Madeleine Fandrich, Meike Jakobi, Armin Manfred Scholz, Stefan Nueske, Nicole Schneiderhan‐Marra, Cécile Gouttefangeas, Manfred Kneilling, Bernd Jürgen Pichler, Dominik Sonanini, Ulrich Rothbauer
This paper develops nanobodies targeting hOX40 for in vivo imaging of activated T cells, showing they bind specifically and function as imaging probes without affecting T cell viability.
Frontiers in Immunology · Oct 15, 2024Peer-reviewedImmunology