Cross-omics profiling reveals cortical neuronal dysfunction following neonatal intraventricular haemorrhage that is attenuated by decorin treatment
Benjamin J. Hewitt, María García‐Bonilla, James Pat McAllister, Simran Pahuja, Grant A. Pellowe, Mackenzie S. Newman, Lauren Roberts, James A. Roberts, Philip Kitchen, Roslyn M. Bill, Lisa J. Hill, Hannah F. Botfield
This study uses cross-omics analysis in a neonatal mouse model of IVH to identify cortical neuronal dysfunction and shows decorin treatment reduces injury by targeting ferroptosis and enhancing microglial phagocytosis.
bioRxiv · Sep 14, 2026 · PreprintNeuroscience