Grant A. Pellowe

This study uses cross-omics analysis in a neonatal mouse model of IVH to identify cortical neuronal dysfunction and shows decorin treatment reduces injury by targeting ferroptosis and enhancing microglial phagocytosis.

The paper investigates how chaperones like Hsp70, Hsp90, and TRiC bind to nascent p53 during translation, showing TRiC's specificity and how mutations affect this process.

The paper investigates how the human ribosome modulates multidomain protein folding by delaying domain docking, contrasting with bacterial ribosomes.

The paper investigates how chaperones coordinate during cotranslational protein folding in bacteria, showing they create a protected space for maturation without destabilizing intermediates.