Author

Siobhan McMahon

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Systems Biology· 2

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:differential expression· 1 Assay:imaging· 1

Frequent Co-Authors

Sarah Filippi· 2 shared Chris P. Barnes· 1 shared Michael P.H. Stumpf· 1 shared Michael Stumpf· 1 shared Oleg Lenive· 1 shared Paul Kirk· 1 shared Shinya KurodaiD· 1 shared Takaho TsuchiyaiD· 1 shared

Activity by Year

2015-2015 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersSystems Biology

Sarah Filippi

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2 papers

Recent·Most cited

Information Processing by Simple Molecular Motifs and Susceptibility to Noise

Siobhan McMahon, Oleg Lenive, Sarah Filippi, Michael Stumpf

The paper quantifies how extrinsic and intrinsic noise affect information transmission in simple molecular motifs and explains how noise can create apparent information.

bioRxiv · Jul 31, 2015Systems Biology

Origins of cell-to-cell variability, kinetic proof-reading and the robustness of MAPK signal transduction

Sarah Filippi, Chris P. Barnes, Paul Kirk, Takamasa Kudo, Siobhan McMahon, Takaho Tsuchiya, Takumi Wada, Shinya Kuroda, Michael P.H. Stumpf

The paper measures cell-to-cell variability in MAPK signaling and shows upstream noise drives ERK phosphorylation heterogeneity, with the system using kinetic proof-reading to robustly transmit signals.

bioRxiv · Jul 1, 2015 · PreprintSystems Biology