ChEC-seq kinetics discriminates transcription factor binding sites by DNA sequence and shape in vivo
Gabriel E. Zentner, Sivakanthan Kasinathan, Beibei Xin, Remo Rohs, Steven Henikoff
This study uses ChEC-seq to identify two classes of transcription factor binding sites in budding yeast based on cleavage kinetics, revealing that DNA sequence and shape influence TF-DNA interactions.
Nature Communications · Oct 22, 2015Peer-reviewedGenomics