Author

Siyu Liu

State Key Laboratory of Reproductive Medicine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biology Disciplines

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Bioinformatics· 1 Genetics· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:mouse· 1 Organism:rat· 1

Frequent Co-Authors

Changjie Yu· 1 shared David Fung· 1 shared Eon S. Lee· 1 shared Guanren Qiao· 1 shared Hua Pei· 1 shared Jack L. Feldman· 1 shared Jing Liang· 1 shared Jingxi Zhang· 1 shared

Activity by Year

2017-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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1 shared paperBioinformatics

Changjie Yu

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3 papers

Recent·Most cited

PerturbTrace: Evaluating Feedback Use by AI Co-Scientist Agents in Perturbation Discovery

Changjie Yu, Siyu Liu, Guanren Qiao, Mingrui Luo, Yujia Xiang, Zhiping XU

PerturbTrace evaluates how AI co-scientist agents use feedback in perturbation discovery, finding that high recall does not imply effective feedback use.

bioRxiv · Aug 20, 2026 · PreprintBioinformatics

Maternal factor PABPN1L is essential for maternal mRNA degradation during maternal-to-zygotic transition

Ying Wang, Tianhao Feng, Xiaodan Shi, Siyu Liu, Zerui Wang, Xin Zhang, Jintao Zhang, Shuqin Zhao, Junqiang Zhang, Xiufeng Ling, Mingxi Liu

This study identifies PABPN1L as essential for maternal mRNA degradation during maternal-to-zygotic transition, with variants linked to female infertility.

bioRxiv · Aug 20, 2020 · PreprintGenetics

Chronic intermittent nicotine delivery with lung alveolar region-targeted aerosol technology produces circadian blood pharmacokinetics in rats resembling human smokers

Xuesi M. Shao, Siyu Liu, Eon S. Lee, David Fung, Hua Pei, Jing Liang, Ross Mudgway, Jingxi Zhang, Jack L. Feldman, Yifang Zhu, Stan Louie, Xinmin S Xie

This paper develops a nicotine aerosol delivery system in rats that mimics human smoking pharmacokinetics, showing similar circadian nicotine and cotinine levels.

bioRxiv · Sep 27, 2017 · PreprintPharmacology & Toxicology