Author

Siyuan Sun

Purdue University West Lafayette

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Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:mouse· 1 Assay:proteomics· 1 Organism:rat· 1 Approach:statistical model· 1

Frequent Co-Authors

Riyi ShiiD· 2 shared Anna Alford· 1 shared Brendan K. BalliD· 1 shared Douglas K. BrubakeriD· 1 shared Rachel L. StingeliD· 1 shared Rachel Stingel· 1 shared Seth Herr· 1 shared Timothy Dong· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 21 mutual co-author links

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2 shared papersNeuroscience

Riyi ShiORCID

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2 papers

Recent·Most cited

Proteomic analysis reveals shared biological pathways linking acrolein to biomolecular changes in the acute phase of rat spinal cord injury

Rachel L. Stingel, Brendan K. Ball, Siyuan Sun, Douglas K. Brubaker, Riyi Shi

The paper uses proteomic analysis to identify acrolein-induced changes in rat spinal cord injury, revealing shared pathways in complement and coagulation cascades.

bioRxiv · Mar 14, 2026 · PreprintNeuroscience

The Pathological Role and Therapeutic potential of ALDH2 in acrolein detoxification Following Spinal Cord Injury in Mice

Riyi Shi, Siyuan Sun, Seth Herr, Anna Alford, Rachel Stingel, Zaiyang Zhang, Timothy Dong

This study investigates ALDH2's role in SCI by genetically impairing and pharmacologically enhancing its activity, showing Alda-1 reduces acrolein levels and improves recovery, especially in ALDH2*2 mice.

bioRxiv · Jun 8, 2025 · PreprintNeuroscience