Riyi Shi

This study develops a human neuronal chimera model to study Alzheimer's tau pathology, showing human-specific vulnerability and recapitulating mature AD features in vivo.

The paper uses proteomic analysis to identify acrolein-induced changes in rat spinal cord injury, revealing shared pathways in complement and coagulation cascades.

This study uses a TBI-on-a-chip model to show that impact injury reduces microglial phagocytosis and alters lipid metabolism, affecting neuroinflammation and neurodegeneration.

This study investigates ALDH2's role in SCI by genetically impairing and pharmacologically enhancing its activity, showing Alda-1 reduces acrolein levels and improves recovery, especially in ALDH2*2 mice.

This paper shows that gene therapies can reduce absence seizures in DBA/2J mice with Scn2a deficiency by restoring NaV1.2 or introducing human KV1.1.

This paper introduces a 3D dual-echo UTE MRI sequence for imaging myelin bilayers, showing higher uT2 fraction in white matter than grey matter.

This study examines auditory system recovery after mild blast trauma in rats over two months, finding multiphasic recovery with persistent central deficits.