BioinformaticsbioRxivPreprint
Improved in situ Characterization of Proteome-wide Protein Complex Dynamics with Thermal Proximity Co-Aggregation
Siyuan Sun, Zhenxiang Zheng, Jun Wang…·Chris Soon Heng Tan
The paper introduces Slim-TPCA, an optimized method for proteome-wide characterization of protein complex dynamics, showing improved throughput and accuracy in identifying complex dissociation and association under glucose deprivation.
DOI 10.1101/2023.02.13.528386