Polygenic Risk for Alcohol Use Disorder Affects Cellular Responses to Ethanol Exposure in a Human Microglial Cell Model
Xindi Li, Jiayi Liu, Andrew J. Boreland, Sneha Kapadia, Siwei Zhang, Alessandro C. Stillitano, Yara Abbo, Lorraine N. Clark, Dongbing Lai, Yunlong Liu, Peter B. Barr, Jacquelyn Leigh Meyers, Chella Kamarajan, Weipeng Kuang, Arpana Agrawal A, , Zhiping P. Pang
This study examines how polygenic risk scores for Alcohol Use Disorder affect microglial responses to ethanol exposure in human iPSC-derived microglia.
Science Advances · Nov 8, 2024Peer-reviewedNeuroscience