Author

Sofia Alves-Vasconcelos

University of Oxford

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Biology Disciplines

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Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Assay:CRISPR screen· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Research Focus:perturbation response prediction· 1 Research Focus:variant effect prediction· 1

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Andrew Bassim HassaniD· 1 shared Joey RiepsaameiD· 1 shared Paul MetziD· 1 shared Richard W. R. Wallbank· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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1 shared paperGenomics

Andrew Bassim HassanORCID

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1 paper

Recent·Most cited

Guide RNA library representation results in gene essentiality prediction bias in genome-wide CRISPR screens

Paul Metz, Sofia Alves-Vasconcelos, Richard W. R. Wallbank, Joey Riepsaame, Andrew Bassim Hassan

This study shows that gRNA library representation bias affects gene essentiality predictions in CRISPR screens, with library choice being the most significant factor.

bioRxiv · Sep 7, 2025 · PreprintGenomics