Serial intravital microscopy reveals temporal dynamics of autoreactive germinal centers in the spleen
Layla Pohl, Thomas Rea Wittenborn, Ali Shahrokhtash, Kristian Savstrup Kastberg, Cecilia Hagert, Lisbeth Jensen, Sofie Andkær Pedersen, Julia Karen Demtröder, Donato Sardella, Alain Pulfer, Duncan S. Sutherland, Santiago F. Gonzalez, Ina Maria Schießl, Søren Egedal Degn
This study uses intravital microscopy to track autoreactive germinal centers in the spleen of live mice over weeks, revealing their dynamic expansion and contraction.
iScience · Mar 11, 2026Peer-reviewedImmunology