Alain Pulfer

This study shows that thymic Treg-derived T follicular regulatory cells prevent autoimmunity by limiting GC responses during TLR7-driven inflammation.

This study uses intravital microscopy to track autoreactive germinal centers in the spleen of live mice over weeks, revealing their dynamic expansion and contraction.

This study shows tattoo ink causes long-term inflammation in lymph nodes and reduces vaccine efficacy against COVID-19.

This study shows that plasmacytoid dendritic cells (pDCs) are critical for both humoral and CD8⁺ T cell memory responses after Pfizer-BioNTech mRNA vaccination.

The paper introduces Immunemap, an open intravital microscopy atlas, and uses unsupervised learning to identify four immune cell motility patterns, including previously uncharacterized behaviors.

This paper introduces ADeS, a deep learning system for detecting apoptosis in live-cell imaging with high accuracy and robustness across diverse conditions.