Author

Kristian Savstrup Kastberg

Aarhus UniversityORCID 0000-0002-4467-2736Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:imaging· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1 Approach:microscopy & imaging analysis· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Ali ShahrokhtashiD· 3 shared Duncan S. SutherlandiD· 3 shared Søren Egedal DegniD· 3 shared Alain PulferiD· 2 shared Cecilia HagertiD· 2 shared Julia Karen Demtröder· 2 shared Layla PohliD· 2 shared Lisbeth JenseniD· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersImmunology

Ali ShahrokhtashORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Thymic Treg-derived T follicular regulatory cells prevent catastrophic humoral autoimmunity in response to TLR7-driven inflammation

Layla Pohl, Lasse Frank Voss, Gudrun Winther, Jensen, Kenneth Green, Yamira C. L. Weber, Julia Karen Demtröder, Cecilia Hagert, Thomas Rea Wittenborn, Chaido Sirinian, Mathias Krogh Pedersen, Johanne Vium-Heinesen, Kristian Savstrup Kastberg, Sofie Vestergaard Fonager, Johannes Skraep, , Søren Egedal Degn

This study shows that thymic Treg-derived T follicular regulatory cells prevent autoimmunity by limiting GC responses during TLR7-driven inflammation.

bioRxiv · Jul 1, 2026 · PreprintImmunology

Serial intravital microscopy reveals temporal dynamics of autoreactive germinal centers in the spleen

Layla Pohl, Thomas Rea Wittenborn, Ali Shahrokhtash, Kristian Savstrup Kastberg, Cecilia Hagert, Lisbeth Jensen, Sofie Andkær Pedersen, Julia Karen Demtröder, Donato Sardella, Alain Pulfer, Duncan S. Sutherland, Santiago F. Gonzalez, Ina Maria Schießl, Søren Egedal Degn

This study uses intravital microscopy to track autoreactive germinal centers in the spleen of live mice over weeks, revealing their dynamic expansion and contraction.

iScience · Mar 11, 2026Peer-reviewedImmunology

Display of clustered antigen by follicular dendritic cells tunes B-cell receptor activation

Ali Shahrokhtash, Hiroaki Ogasawara, Kristian Savstrup Kastberg, Khalid S. Salaita, Søren Egedal Degn, Duncan S. Sutherland

The paper shows that antigen clustering on follicular dendritic cells enhances B-cell receptor activation through geometric control of tyrosine phosphatase exclusion.

bioRxiv · Nov 5, 2025 · PreprintImmunology