Accurate and scalable multi-disease classification from adaptive immune repertoires
Natnicha Jiravejchakul, Ayan Sengupta, Songling Li, Debottam Upadhyaya, Mara Anaís Llamas-Covarrubias, Florian Hauer, Soichiro Haruna, Daron M. Standley
This paper introduces FACTS, a scalable machine learning framework for multi-disease classification using TCR repertoires, achieving high accuracy and preserving biological signals.
bioRxiv · Aug 12, 2025 · PreprintBioinformatics