Coupled nucleoplasmic flows and envelope expansion govern the mechanical resistance of the nucleus
Romain Rollin, Michele M. Nava, Alice Williart, Solene Ludwig, Camille N. Plancke, Marie‐Aude Plamont, Mabel J. Jouve, Guilherme P. F. Nader, Zoher Gueroui, Jean‐François Joanny, Daniel J. Müller, Damien Cuvelier, Pierre Sens, Matthieu Piel
This study proposes a physical model of the nucleus that explains its mechanical behavior under deformation, highlighting the role of the envelope and chromatin in nuclear mechanics.
bioRxiv · Jun 13, 2026 · PreprintBiophysics