Cerebellar induced VTA plasticity underlies chronic stress-induced depression-like behaviors
Seulgi Kang, Taehyeong Kim, Daun Kim, Soo-Ji Baek, Thomas John McHugh, Yukio Yamamoto, Keiko Tanaka
This study identifies VGLUT2 reduction in VTAp-DCN axons as a mechanism linking chronic stress to depression-like behaviors through impaired dopamine signaling.
bioRxiv · May 8, 2026 · PreprintNeuroscience