Author

Sophia Hofmeister

University of California San Diego

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Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Assay:ChIP-seq· 1 Approach:mixed model· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Elizabeth A. KomivesiD· 1 shared Hannah E.R. BaughmaniD· 1 shared Luke SebastianiD· 1 shared Neville P. BetheliD· 1 shared Tristan R. GuntheriD· 1 shared

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2026-2026 · peak 1/yr

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1 shared paperBiochemistry

Elizabeth A. KomivesORCID

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1 paper

Recent·Most cited

BiochemistrybioRxivPreprintOct 29, 2026

Optimization of the NFκB-DNA ensemble leads to high affinity binding of partial consensus sites

Tristan R. Gunther, Sophia Hofmeister, Luke Sebastian…·Elizabeth A. Komives

The paper investigates how NFκB (RelA/p50) achieves high-affinity binding to partial consensus DNA sequences through structural rearrangements and dynamic interactions.

DOI 10.64898/2026.10.26.762037

ChIP-seqmixed model

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