Author

Sophia K Tan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Assay:protein structure· 1 Approach:statistical model· 1

Frequent Co-Authors

Alan AshworthiD· 1 shared Dimitrios Gazgalis· 1 shared Hyunil JoiD· 1 shared Hyunjun YangiD· 1 shared Jesús Valdiviezo· 1 shared Lei LuiD· 1 shared Morgan E. DiolaitiiD· 1 shared Nicholas F. PolizziiD· 1 shared

Activity by Year

2023-2023 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperBiophysics

Alan AshworthORCID

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1 paper

Recent·Most cited

BiophysicsbioRxivPreprintDec 23, 2023

De novo design of drug-binding proteins with predictable binding energy and specificity

Lei Lu, Xuxu Gou, Sophia K Tan…·William F. DeGrado

This paper designs drug-binding proteins with low nanomolar affinity and predictable specificity using computational methods, validated by experimental measurements and structural analysis.

DOI 10.1101/2023.12.23.573178

protein structuredeep learning

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