Stem-cell niche self-restricts the signaling range via receptor-ligand degradation
Sophia Ladyzhets, Matthew Antel, Taylor Simao, Nathan S. Gasek, Ann E. Cowan, Mayu Inaba
The paper shows that MT-nanotubes in Drosophila GSCs restrict niche signaling range by enabling specific receptor-ligand interaction and subsequent degradation of the signaling components.
PLoS Biology · Dec 14, 2020Peer-reviewedDevelopmental Biology