The establishment of variant surface glycoprotein monoallelic expression revealed by single-cell RNA-seq of Trypanosoma brucei in the tsetse fly salivary glands.
Sebastian Hutchinson, Sophie Foulon, Aline Crouzols, Roberta Menafra, Brice Rotureau, Andrew D. Griffiths, Philippe Bastin
This study uses scRNA-seq to analyze Trypanosoma brucei development in tsetse fly salivary glands, revealing dynamic VSG gene activation and monoallelic expression establishment.
PLoS Pathogens · Sep 20, 2021Peer-reviewedMolecular Biology