Aline Crouzols

Gnotobiotic OMM12 mice support sustained Clostridioides difficile colonization without antibiotic pretreatment

This study shows that gnotobiotic OMM12 mice can sustain Clostridioides difficile colonization for 20 days without antibiotic pretreatment, allowing research on host-microbiota-pathogen interactions.

Clostridioides difficile binary toxin CDT induces biofilm-like persisting microcolonies

This study shows that CDT toxin from Clostridioides difficile induces biofilm-like microcolonies, increasing colonization and persistence in intestinal models and infected mice.

In vitro biofilms of Clostridioides difficile undomesticated strains: Morphology and properties according to strain diversity

This study examines biofilm formation and properties of C. difficile undomesticated strains, finding that ribotype 009 strains form highly adhesive biofilms and show increased vancomycin tolerance.

Oxidative phosphorylation is required for powering motility and development of the sleeping sickness parasite Trypanosoma brucei within the tsetse fly vector

This study shows that oxidative phosphorylation is essential for Trypanosoma brucei migration within tsetse flies but not for initial colonization.

The establishment of variant surface glycoprotein monoallelic expression revealed by single-cell RNA-seq of Trypanosoma brucei in the tsetse fly salivary glands.

This study uses scRNA-seq to analyze Trypanosoma brucei development in tsetse fly salivary glands, revealing dynamic VSG gene activation and monoallelic expression establishment.