Author

Sophie M. Whitehead

University of Colorado Boulder

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Molecular Biology· 1

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Approach:experimental assay· 1

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Benjamin Guy BitleriD· 1 shared Erin Taylor· 1 shared Nausica ArnoultiD· 1 shared Raquel OrtegaiD· 1 shared Thomas DanhorniD· 1 shared

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Benjamin Guy BitlerORCID

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1 paper

Recent·Most cited

Molecular BiologybioRxivPreprintJun 9, 2025

PARP1 and PARP2 are dispensable for DNA repair by microhomology-mediated end-joining during mitosis.

Raquel Ortega, Erin Taylor, Sophie M. Whitehead…·Nausica Arnoult

This study shows PARP1 and PARP2 are not required for MMEJ during mitosis, challenging previous assumptions and supporting combinatorial PARPi/MMEJi therapy in HR-deficient cancers.

DOI 10.1101/2025.06.09.658719

experimental assay

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