DOT1L bridges transcription and heterochromatin formation at pericentromeres
Aushaq Bashir Malla, Haoming Yu, Delaney Farris, Srilekha Kadimi, TuKiet T. Lam, Andy L Cox, Zachary D. Smith, Bluma J. Lesch
This study shows that DOT1L is essential for transcription of pericentromeric repeats and maintains genome stability by bridging transcription and heterochromatin formation.
EMBO Reports · Jun 15, 2023Peer-reviewedMolecular Biology