Haoming Yu

The paper shows that paternal KDM6A loss disrupts H3K4 methylation at tumor suppressor gene promoters, increasing cancer risk in offspring.

The paper shows that humanized Traf6 promoter sequences in mice affect immune responses but not fertility, revealing distinct roles for germ and immune cells in gene regulatory evolution.

The paper investigates the role of H3K4me3 at intergenic regulatory elements and finds it instructs RNA polymerase activity and is actively remodeled.

This study shows that DOT1L is essential for transcription of pericentromeric repeats and maintains genome stability by bridging transcription and heterochromatin formation.