Author

Aushaq Bashir Malla

Yale UniversityORCID 0000-0001-5733-6523Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:ChIP-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Bluma J. LeschiD· 2 shared Andy L CoxiD· 1 shared Benjamin William WaltersiD· 1 shared Delaney FarrisiD· 1 shared Haoming YuiD· 1 shared Kira Lynn MarshalliD· 1 shared Rachel A. HeueriD· 1 shared Shannon R RainsfordiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersGenetics

Bluma J. LeschORCID

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2 papers

Recent·Most cited

GeneticsProceedings of the National Academy of SciencesPeer-reviewedJul 31, 2025

ISWI chromatin remodeler SMARCA5 is essential for meiotic gene expression and male fertility in mammals

Shubhangini Kataruka, Aushaq Bashir Malla, Shannon R Rainsford…·Bluma J. Lesch

This study shows that SMARCA5 is essential for meiotic gene expression and male fertility by regulating chromatin accessibility during spermatogenesis.

10 citationstop 2%

mousebulk RNA-seq

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Molecular BiologyEMBO ReportsPeer-reviewedJun 15, 2023

DOT1L bridges transcription and heterochromatin formation at pericentromeres

Aushaq Bashir Malla, Haoming Yu, Delaney Farris…·Bluma J. Lesch

This study shows that DOT1L is essential for transcription of pericentromeric repeats and maintains genome stability by bridging transcription and heterochromatin formation.

19 citations

mouseDNA methylation

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