Patient-Derived Three-Dimensional Lung Tumor Models to Evaluate Response to Immunotherapy
Kayla F. Goliwas, Kenneth P. Hough, Sruti Sivan, Sierra L. Single, Sameer S. Deshmukh, Joel L. Berry, Maya Khalil, Benjamin Wei, Yanis Boumber, Mohammad Athar, Aakash P. Desai, Selvarangan Ponnazhagan, James Donahue, Jessy S. Deshane
The paper develops a 3D lung tumor model to evaluate immunotherapy response and identifies biomarkers for predicting immune checkpoint inhibitor efficacy in NSCLC.
bioRxiv · May 19, 2025 · PreprintCancer Biology