Nuclear exosome targeting complexes modulate cohesin binding and enhancer-promoter interactions in 3D
Charbel Akkawi, Alexandre Heurteau, Xavier Contreras, Marion Helsmoortel, Stéphane Schaak, Julie Bossuyt, Olivier Fosseprez, David Depierre, Olivier Cuvier, Rosemary E. Kiernan
The paper shows that nuclear RNA exosome complexes regulate enhancer-promoter interactions by modulating ncRNA levels and cohesin binding.
Nature Communications · Aug 6, 2026Peer-reviewedMolecular Biology