Author

Alexandre Heurteau

Centre National de la Recherche ScientifiqueORCID 0000-0002-1981-590XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Molecular Biology· 3 Genomics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:differential expression· 4 Organism:human· 4 Approach:statistical model· 4 Assay:bulk RNA-seq· 3 Research Focus:gene regulatory network inference· 3 Assay:ChIP-seq· 2 Approach:experimental assay· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Olivier CuvieriD· 4 shared David DepierreiD· 3 shared Charbel AkkawiiD· 2 shared Marion HelsmoorteliD· 2 shared Rosemary E. KiernaniD· 2 shared Xavier ContrerasiD· 2 shared Ahmad YatimiD· 1 shared Anne-Claire LavigneiD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersMolecular Biology

Olivier CuvierORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Nuclear exosome targeting complexes modulate cohesin binding and enhancer-promoter interactions in 3D

Charbel Akkawi, Alexandre Heurteau, Xavier Contreras, Marion Helsmoortel, Stéphane Schaak, Julie Bossuyt, Olivier Fosseprez, David Depierre, Olivier Cuvier, Rosemary E. Kiernan

The paper shows that nuclear RNA exosome complexes regulate enhancer-promoter interactions by modulating ncRNA levels and cohesin binding.

Nature Communications · Aug 6, 2026Peer-reviewedMolecular Biology

PAP-gamma associates with PAXT nuclear exosome to control the abundance of PROMPT ncRNAs

Xavier Contreras, David Depierre, Charbel Akkawi, Marina Srbić, Marion Helsmoortel, Maguelone Nogaret, Matthieu Le Hars, Kader Salifou, Alexandre Heurteau, Olivier Cuvier, Rosemary E. Kiernan

The paper identifies PAP-gamma as a component of the PAXT complex that recruits it to gene promoters, regulating PROMPT ncRNA abundance through polyadenylation.

Nature Communications · Oct 24, 2023Peer-reviewedMolecular Biology

The histone variant macroH2A1.1 regulates RNA Polymerase II paused genes within defined chromatin interaction landscapes.

Ludmila Recoules, Alexandre Heurteau, Flavien Raynal, Nezih Karasu, Fatima Moutahir, Fabienne Bejjani, Isabelle Jariel‐Encontre, Olivier Cuvier, Tom Sexton, Anne-Claire Lavigne, Kerstin Bystricky

This study identifies mH2A1.1's role in regulating RNA Polymerase II paused genes through distinct chromatin mechanisms in breast cancer cells.

Journal of Cell Science · Apr 1, 2022Peer-reviewedGenomics

NOTCH assembles a transcriptional repressive complex containing NuRD and PRC1 to repress genes involved in cell proliferation and differentiation.

Cécile M. Doyen, David Depierre, Ahmad Yatim, Alexandre Heurteau, Jean‐Daniel Lelièvre, Yves Lévy, Olivier Cuvier, Monsef Benkirane

bioRxiv · Jan 15, 2019 · PreprintMolecular Biology