Xavier Contreras

The paper shows that nuclear RNA exosome complexes regulate enhancer-promoter interactions by modulating ncRNA levels and cohesin binding.

This study identifies NRDE2 interactions with transcription and splicing factors and shows its broad impact on gene expression and splicing in human cells.

This study identifies Limch1+/Prg4+ adipose stromal cells as mobilizable cells that contribute to muscle regeneration through transient adipogenic differentiation.

This paper shows that increasing Med19 in Drosophila extends lifespan by 90%, delays frailty onset, and improves stress resistance, while reducing Med19 shortens lifespan and increases vulnerability to stress.

The paper identifies PAP-gamma as a component of the PAXT complex that recruits it to gene promoters, regulating PROMPT ncRNA abundance through polyadenylation.

The paper identifies the MRN complex's role in protecting actively transcribing genes from genomic instability through transcriptional association.