THO and TRAMP complexes prevent transcription-replication conflicts, DNA breaks, and CAG repeat contractions
Rebecca E. Brown, Xiaofeng A. Su, Stacey Fair, Katherine Wu, Lauren Verra, Robyn M. Jong, Kristin R. Andrykovich, Catherine H. Freudenreich
This study shows that THO and TRAMP complexes prevent CAG repeat instability by reducing RNA polymerase stalling and transcription-replication conflicts in yeast.
PLoS Biology · Dec 27, 2022Peer-reviewedGenetics