Xiaofeng A. Su

Streamline CNV is a Nextflow pipeline for CNV analysis that simplifies processing, visualization, and interpretation of copy number data across various sequencing types and species.

SpotMAX is an AI-driven framework for automated spot detection and quantification in microscopy data, outperforming existing tools and human annotators across diverse biological applications.

This study identifies CRY1 as a stage-specific regulator of DNA damage repair in prostate cancer, showing it promotes NHEJ/BER in hormone-sensitive disease and HR in castration-resistant disease.

This study uses proteogenomics to identify ancestry-specific and shared molecular drivers in prostate cancer, revealing distinct biological programs and improving risk prediction.

This study identifies CBP/p300 as critical for DNA repair in prostate cancer and shows that targeting it enhances therapeutic response.

This study shows that THO and TRAMP complexes prevent CAG repeat instability by reducing RNA polymerase stalling and transcription-replication conflicts in yeast.