Author

Stacey Fluke

Hospital for Sick Children

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Cell Biology· 1

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Organism:C. elegans· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Research Focus:metabolism & bioenergetics· 1

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Bin Yu· 1 shared Maria QuintanaiD· 1 shared Rachel WebsteriD· 1 shared Ran KafriiD· 1 shared W. Brent DerryiD· 1 shared

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2025-2025 · peak 1/yr

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1 shared paperCell Biology

Bin Yu

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1 paper

Recent·Most cited

Cell BiologyHeredityPeer-reviewedMay 18, 2025

CDK-4 regulates nucleolar size and metabolism at the cost of late life fitness in C. elegans

Rachel Webster, Maria Quintana, Bin Yu…·W. Brent Derry

This study shows that CDK-4 in C. elegans regulates nucleolar size and metabolism, leading to improved early life thermotolerance but reduced longevity.

DOI 10.1038/s41437-025-00769-7

C. elegansexperimental assay

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