The mouse Klf1 Nan variant impairs nuclear condensation and erythroid maturation
Ileana Cantú, Harmen J.G. van de Werken, Nynke Gillemans, Ralph Stadhouders, Steven Heshusius, Alex Maas, Fatemehsadat Esteghamat, Zeliha Özgür, Wilfred F. J. van IJcken, Frank G. Grosveld, Marieke v. Lindern, Sjaak Philipsen, Thamar B. van Dijk
The paper investigates the effects of the Klf1 Nan variant on erythroid maturation, finding that it causes nuclear condensation defects and deregulates Xpo7 expression.
PLoS ONE · Mar 28, 2019Peer-reviewedDevelopmental Biology