Author
Erasmus MCORCID 0000-0002-9794-1477Unclaimed ORCID profile · follow to get notified of new preprints
7 papers
Recent·Most cited
Tong Yang, Joke Veldhoven-Zweistra, Maarten Ligtenberg…·Guido W Jenster
This study demonstrates that non-targeted immunization and panning can isolate PSMA-targeting nanobodies from phage display libraries.
Kou Hioki, Marlous Wildemans, Youkyung Lim…·Peter D. Katsikis
This study demonstrates that Prime-Target neoantigen vaccination effectively overcomes immunosuppression in 'cold' tumors by enhancing T cell infiltration and reshaping the tumor microenvironment.
Daan M. Hazelaar, Job van Riet, Youri Hoogstrate, Harmen J.G. van de Werken
Katdetectr detects kataegis loci in genomic data using unsupervised changepoint analysis, showing high accuracy and speed compared to existing tools.
Wesley S. van de Geer, Job van Riet, Harmen J.G. van de Werken
ProteoDisco generates customized protein databases for proteogenomic studies by incorporating genomic variants and transcriptomic data into protein sequences.
Youri Hoogstrate, Guido W Jenster, Harmen J.G. van de Werken
FASTAFS provides a filesystem virtualization solution for compressed FASTA files, enabling fast random access and metadata management.
Youri Hoogstrate, Malgorzata A. Komor, René Böttcher…·Guido W Jenster
Dr. Disco identifies fusion transcripts and genomic breakpoints using non poly(A)-enriched RNA-seq data, revealing transcribed rearrangements and their expression effects in cancer samples.
Ileana Cantú, Harmen J.G. van de Werken, Nynke Gillemans…·Thamar B. van Dijk
The paper investigates the effects of the Klf1 Nan variant on erythroid maturation, finding that it causes nuclear condensation defects and deregulates Xpo7 expression.