In vitro evolution of caspofungin resistance in Candidozyma auris via FKS1 hotspot I mutations results in moderate fitness trade-offs but no reduction in virulence
Zoe K. Ross, Sakinah Alsayegh, Yixin Zhao, Steven McPherson, Carol A. Munro, Alexander Lorenz
This study shows that FKS1-S639 mutations confer caspofungin resistance in C. auris but cause moderate fitness trade-offs without reducing virulence.
Microbiological Research · Aug 20, 2025Peer-reviewedMicrobiology