Low abundance of circulating tumor DNA in localized prostate cancer
S. Thomas Hennigan, Shana Y. Trostel, Nicholas Taylor Terrigino, Olga S. Voznesensky, Rachel J. Schaefer, Nichelle C. Whitlock, Scott C. Wilkinson, Nicole V. Carrabba, Rayann Atway, Steven Shema, Ross G. Lake, Amalia R. Sweet, David Johnson Einstein, Fatima H. Karzai, James L. Gulley, , Adam G. Sowalsky
The paper shows that ctDNA is undetectable in localized prostate cancer but present in metastatic cases, suggesting lower dissemination and detectability in early stages.
JCO Precision Oncology · Sep 9, 2019Peer-reviewedGenomics