Author

Subrahmanyam Vangala

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:host-pathogen & immune response· 1 Assay:protein structure· 1

Frequent Co-Authors

K Saranya· 3 shared Kranti Meher· 3 shared Uday Saxena· 3 shared Gopi Kadiyala· 2 shared R.N Arpitha Reddy· 2 shared Satish Chandran· 2 shared Subramanian Iyer· 2 shared Sanjana Battula· 1 shared

Activity by Year

2023-2023 · peak 3/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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3 shared papersPharmacology & Toxicology

K Saranya

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3 papers

Recent·Most cited

Pharmacology & ToxicologybioRxivPreprintAug 29, 2023

Robust acidic pH and digestive enzyme stability of anti-SarsCov2 IgY antibodies: Implications for treatment of viral transmission thru gastrointestinal, ocular, nasal and skin tissues

Sanjana Battula, K Saranya, Kranti Meher…·Uday Saxena

The paper evaluates the stability of anti-SARS-CoV-2 IgY antibodies at acidic pH and against trypsin digestion, supporting their use in treating viral transmission through acidic environments.

2 citations

protein structureexperimental assay

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Pharmacology & ToxicologybioRxivPreprintMay 14, 2023

Metformin an anti-diabetic drug, possess ACE-2 receptor-SARS- Cov-2 RBD binding antagonist activity, anti-inflammatory and cytokine inhibitory properties suitable for treatment of COVID-19

Uday Saxena, Kranti Meher, K Saranya, Subrahmanyam Vangala

This study shows metformin blocks SARS-CoV-2 RBD-ACE2 binding, reduces inflammation, and has anti-inflammatory effects in a hamster model, suggesting it could be used as a nasal spray for COVID-19 treatment.

1 citation

mouseproteomics

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Pharmacology & ToxicologybioRxivPreprintMay 6, 2023

Targeted neutralizing IgY antibodies against SGLT1 glucose transporter reduce glucose uptake and improve glycemic profile in vivo

Uday Saxena, Kranti Meher, R.N Arpitha Reddy…·Satish Chandran

DOI 10.1101/2023.05.06.539723

mouseproteomics

𝕏 PostBluesky