Author

Sunayana Malla

University of Nebraska–Lincoln

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Cancer Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 5 Organism:human· 4 Assay:bulk RNA-seq· 3 Research Focus:metabolism & bioenergetics· 3 Research Focus:host-pathogen & immune response· 2 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Rajib SahaiD· 5 shared Ratul ChowdhuryiD· 2 shared A. PeeriD· 1 shared Bibek AcharyaiD· 1 shared Daren L. KnoelliD· 1 shared Deandra R. Smith· 1 shared Derrick R. SamuelsoniD· 1 shared Karuna Anna SajeevaniD· 1 shared

Activity by Year

2024-2026 · peak 4/yr

Co-Author Collaboration Network

9 top collaborators · 18 mutual co-author links

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Curved chords = mutual co-authorship

5 shared papersImmunology

Rajib SahaORCID

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Thermodynamic Quality Control Reshapes Spatially Resolved Metabolic Flux Predictions in Prostate Cancer

Mohammad Reza Zargar, Sunayana Malla, Rajib Saha, Ratul Chowdhury

Quality-controlled, cycle-certified E-Flux Human-GEM models of twelve regions from one prostate tumor curb implementation-driven flux inflation and show predicted metabolic similarity tracks spatial region, not histology.

bioRxiv · Oct 21, 2026 · PreprintCancer Biology✦ In-depth digest

Solute Carrier Transporter Family Modulates Neutrophil Metabolism During Health and Disease

Sunayana Malla, Rajib Saha

This study identifies metabolic reprogramming in neutrophils under stress conditions and highlights the role of solute carrier transporters in metabolic specialization.

bioRxiv · May 22, 2026 · PreprintImmunology

A Closed Computational - Experimental Loop Identifies Metabolic Collapse at the Root of Macrophage Dysfunction due to Zinc Dyshomeostasis

Sunayana Malla, Deandra R. Smith, A. Peer, Derrick R. Samuelson, Daren L. Knoell, Rajib Saha

This study identifies metabolic collapse due to zinc dyshomeostasis in macrophages, showing succinate and kynurenic acid can restore immune function.

bioRxiv · Jan 11, 2026 · PreprintImmunology

Pathway Thermodynamic Analysis Postulates Change in Glutamate Metabolism as a Key Factor in Modulating Immune Responses

Sunayana Malla, Rajib Saha

This study uses MDF analysis to examine how temperature changes affect metabolic pathway thermodynamics, identifying glutamate metabolism as a key factor in immune response modulation.

Immunometabolism · Jan 1, 2026Peer-reviewedImmunology

Dissecting Metabolic Landscape of Alveolar Macrophage

Sunayana Malla, Karuna Anna Sajeevan, Bibek Acharya, Ratul Chowdhury, Rajib Saha

This study investigates metabolic shifts in alveolar macrophages during M1 and M2 activation phases, highlighting non-central carbon metabolism pathways and temperature's role in immune response.

Scientific Reports · Dec 5, 2024Peer-reviewedSystems Biology