Functional promoter polymorphisms govern the differential expression of HMG-CoA Reductase gene in rat models of essential hypertension
Abrar Ali Khan, Sundar Poovitha, Vinayak Gupta, Vikas Arige, Sukka Santosh Reddy, Madhu Dikshit, Manoj Kumar Barthwal, Nitish R. Mahapatra
The paper identifies promoter polymorphisms in the Hmgcr gene that reduce its expression in rat hypertension models by altering transcription factor binding.
bioRxiv · Apr 19, 2019 · PreprintMolecular Biology