Author

Abrar Ali Khan

Indian Institute of Technology Madras

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 3

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Approach:statistical model· 3 Organism:rat· 2 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Manoj Kumar BarthwaliD· 3 shared Nitish R. MahapatraiD· 3 shared Sukka Santosh Reddy· 3 shared Vikas ArigeiD· 3 shared Bhargavi NatarajaniD· 2 shared Vinayak GuptaiD· 2 shared B. K. Chandrasekhar SagariD· 1 shared Heena Agarwal· 1 shared

Activity by Year

2019-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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3 shared papersMolecular Biology

Manoj Kumar BarthwalORCID

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3 papers

Recent·Most cited

MicroRNA-27a is a key modulator of cholesterol biosynthesis

Abrar Ali Khan, Heena Agarwal, Sukka Santosh Reddy, Vikas Arige, Bhargavi Natarajan, Vinayak Gupta, Kalyani Ananthamohan, Manoj Kumar Barthwal, Nitish R. Mahapatra

This study identifies miR-27a as a regulator of Hmgcr and cholesterol biosynthesis, showing its role in modulating plasma cholesterol levels in mice.

Molecular and Cellular Biology · Feb 17, 2020Peer-reviewedMolecular Biology

Hypoxia mediated regulation of mitochondrial transcription factors: Implications of hypertensive renal physiology

Bhargavi Natarajan, Vikas Arige, Abrar Ali Khan, Sukka Santosh Reddy, Rashmi Santhoshkumar, B. K. Chandrasekhar Sagar, Manoj Kumar Barthwal, Nitish R. Mahapatra

This study investigates how hypoxia regulates mitochondrial transcription factors in hypertensive rats and cultured kidney cells, finding increased expression of HIF-1, PGC-1, mtTFs, and OXPHOS proteins under hypoxic conditions.

bioRxiv · Jan 28, 2020 · PreprintMolecular Biology

Functional promoter polymorphisms govern the differential expression of HMG-CoA Reductase gene in rat models of essential hypertension

Abrar Ali Khan, Sundar Poovitha, Vinayak Gupta, Vikas Arige, Sukka Santosh Reddy, Madhu Dikshit, Manoj Kumar Barthwal, Nitish R. Mahapatra

The paper identifies promoter polymorphisms in the Hmgcr gene that reduce its expression in rat hypertension models by altering transcription factor binding.

bioRxiv · Apr 19, 2019 · PreprintMolecular Biology