Nitish R. Mahapatra

Dynamic regulation of cystathionine gamma-lyase expression during normoxia, ischemia, and reperfusion in liver: interplay of transcription factors, microRNAs, and histone modifications

This study identifies the molecular mechanisms regulating CTH expression during ischemia and reperfusion, revealing the roles of transcription factors, microRNAs, and histone modifications.

MicroRNA-27a is a key modulator of cholesterol biosynthesis

This study identifies miR-27a as a regulator of Hmgcr and cholesterol biosynthesis, showing its role in modulating plasma cholesterol levels in mice.

Hypoxia mediated regulation of mitochondrial transcription factors: Implications of hypertensive renal physiology

This study investigates how hypoxia regulates mitochondrial transcription factors in hypertensive rats and cultured kidney cells, finding increased expression of HIF-1, PGC-1, mtTFs, and OXPHOS proteins under hypoxic conditions.

Functional promoter polymorphisms govern the differential expression of HMG-CoA Reductase gene in rat models of essential hypertension

The paper identifies promoter polymorphisms in the Hmgcr gene that reduce its expression in rat hypertension models by altering transcription factor binding.

A common tag nucleotide variant in MMP7 promoter increases risk for hypertension via enhanced interactions with CREB transcription factor

This study identifies a SNP in the MMP7 promoter that increases hypertension risk by enhancing CREB binding and MMP7 expression under stress conditions.