Isocaloric restriction of a high-fat diet under TAK-242 administration: metabolic and gut microbial responses in mice
Eunji Jeong, Seoyeon Chae, Sungjin Eun, Hyunwoo Chai, Sunhye Lee
This study examines the effects of isocaloric high-fat diet restriction with TAK-242 on metabolic and gut microbial responses in mice, finding limited normalization of adiposity and microbial community.
bioRxiv · Nov 6, 2026 · PreprintPhysiology