Eunji Jeong

Isocaloric restriction of a high-fat diet under TAK-242 administration: metabolic and gut microbial responses in mice

This study examines the effects of isocaloric high-fat diet restriction with TAK-242 on metabolic and gut microbial responses in mice, finding limited normalization of adiposity and microbial community.

Isocaloric restriction normalizes body weight but not relative adiposity, adipose inflammation, or gut microbial diversity in high-fat diet-fed mice