Production of systemically circulating Hedgehog by the intestine couples nutrition to growth and development
Jonathan Rodenfels, Oksana Lavrynenko, Sophie Ayciriex, Julio L Sampaio, Maria Carvalho, Andrej Shevchenko, Suzanne Eaton
This study shows that the intestine produces systemic Hedgehog in Drosophila larvae, linking nutrition to growth and developmental timing through hormonal signaling.
bioRxiv · Nov 3, 2014Developmental Biology