Sophie Ayciriex

This study identifies N-acetyl-phenylalanine (NAPA) as a metabolite that promotes hepatic steatosis in MASLD by disrupting ER-mitochondria calcium coupling and mitochondrial lipid oxidation.

This study reconstructs the metabolic pathways of the amphipod Gammarus fossarum using multi-omics data, revealing organ-specific metabolic profiles and validating enzyme expression through proteomics.

The paper uses DIA-MS/MS with Zeno trap and EAD to analyze lipidome and metabolome of amphipods during molting, identifying key molecular changes and improving compound identification through machine learning.

The paper investigates how dietary lipid manipulations affect the Drosophila eye proteome and identifies lipid-responsive proteins involved in muscle function and stress responses.

The paper quantifies the proteome of the Drosophila melanogaster eye using GeLC-MS/MS and provides a resource for further studies.

This study shows that the intestine produces systemic Hedgehog in Drosophila larvae, linking nutrition to growth and developmental timing through hormonal signaling.