Exosome-like biogenesis from the Golgi releases extracellular vesicles lacking conventional tetraspanins that mediate immune evasion in cancer
Ikjot Singh Sohal, Sydney N. Shaw, Andrea P dos Santos, Bennett D. Elzey, Haley Anne Harper, Carli J. McMahan, Lauren N. Meeks, Humna Hasan, Zulaida Soto-Vargas, Noor Abdullah, Subhransu Sahoo, Majid Kazemian, Matthew Richard Olson, Andrea L. Kasinski
This study identifies TGOLN2-driven extracellular vesicles from the Golgi that suppress T cell function and are associated with poor cancer survival.
bioRxiv · May 13, 2026 · PreprintCell Biology