Genetic association analyses highlight IL6, ALPL, and NAV1 as three new susceptibility genes underlying calcific aortic valve stenosis
Sébastien Thériault, Christian Dina C, David Messika–Zeitoun, Solena Le Scouarnec, Romain Capoulade, Nathalie Gaudreault, Sidwell Rigade, Zhonglin Li, Floriane Simonet, Maxime Lamontagne, Marie-Annick A Clavel, Benoît J. Arsenault, Anne‐Sophie Boureau, Simon Lecointe, Estelle Baron, , Sylviane Vol
This study identifies three new susceptibility genes for calcific aortic valve stenosis through GWAS and TWAS, highlighting roles in inflammation, mineralization, and blood vessel integrity.
Circulation Genomic and Precision Medicine · Oct 1, 2019Peer-reviewedGenomics