Author

Romain Capoulade

Centre National de la Recherche ScientifiqueORCID 0000-0002-7233-7409Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Genomics· 2 Cell Biology· 1 Genetics· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 4 Approach:statistical model· 4 Assay:bulk RNA-seq· 2 Research Focus:drug response / drug discovery· 2 Research Focus:GWAS / association mapping· 2 Assay:electronic health records· 1 Approach:experimental assay· 1 Assay:GWAS summary statistics· 1

Frequent Co-Authors

Marie-Annick A ClaveliD· 3 shared Patrick MathieuiD· 3 shared Philippe PîbarotiD· 3 shared Sébastien ThériaultiD· 3 shared Yohan BosséiD· 3 shared Benoît J. ArsenaultiD· 2 shared Christian Dina CiD· 2 shared David Messika–ZeitouniD· 2 shared

Activity by Year

2018-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersGenomics

Marie-Annick A ClavelORCID

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

In vivo optical induction of INaL by photoactivation of AaH-II peptide in beating heart using wireless implantable device

Matthias Dereli, Hugo Millet, Agnès Hivonnait, Antoine Persello, Maureen Choteau‐Bodor, Virginie Aillerie, Pascal Aumond, Claude Zoukimian, Edith Bigot, Rémy Béroud, Romain Capoulade, Philipp Gutruf, Flavien Charpentier, Michel MDW DE WAARD, Jérôme Montnach

This paper demonstrates wireless photoactivation of a peptide to modulate cardiac excitability in vivo using an implantable device.

bioRxiv · Oct 28, 2026 · PreprintPharmacology & Toxicology

Sirtuin 1 modulation unlocks the therapeutic potential of sodium-glucose co-transporter 2 inhibitors (SGLT2i) in calcific aortic valve stenosis

Vincenza Valerio, Ilaria Massaiu, Matteo Franchi, Antoine Rimbert, Zoé Begué-Racapé, Mattia Chiesa, Veronika A. Myasoedova, Valentina Rusconi, Francesca Bertolini, Donato De Giorgi, Alice Bonomi, Sergio Pirola, Marco Zanobini, Paola Di Pietro, Albino Carrizzo, , Paolo Poggio

This study shows SIRT1 regulates calcific aortic valve stenosis progression and that SGLT2i may slow valve degeneration by modulating SIRT1.

Cardiovascular Research · Sep 5, 2026Peer-reviewedCell Biology

Genetic association analyses highlight IL6, ALPL, and NAV1 as three new susceptibility genes underlying calcific aortic valve stenosis

Sébastien Thériault, Christian Dina C, David Messika–Zeitoun, Solena Le Scouarnec, Romain Capoulade, Nathalie Gaudreault, Sidwell Rigade, Zhonglin Li, Floriane Simonet, Maxime Lamontagne, Marie-Annick A Clavel, Benoît J. Arsenault, Anne‐Sophie Boureau, Simon Lecointe, Estelle Baron, , Sylviane Vol

This study identifies three new susceptibility genes for calcific aortic valve stenosis through GWAS and TWAS, highlighting roles in inflammation, mineralization, and blood vessel integrity.

Circulation Genomic and Precision Medicine · Oct 1, 2019Peer-reviewedGenomics

Genetic inhibition of PCSK9, atherogenic lipoprotein concentrations, and calcific aortic valve stenosis

Nicolas Perrot, Donato Moschetta, S. Matthijs Boekholdt, Vincenza Valerio, Andreas Martinsson, Romain Capoulade, Elvira Mass, Marie-Annick A Clavel, Nicholas J. Wareham, Christian Dina C, Hao Yu Chen, James C. Engert, George Thanassoulis, Patrick Mathieu, Yohan Bossé, , Benoît J. Arsenault

This study shows genetic inhibition of PCSK9 lowers lipoprotein levels and reduces risk of CAD and CAVS, with PCSK9 present in calcified aortic valves and induced by oxidative stress.

bioRxiv · Mar 1, 2019 · PreprintGenetics

A transcriptome-wide association study identifies PALMD as a susceptibility gene for calcific aortic valve stenosis

Sébastien Thériault, Nathalie Gaudreault, Maxime Lamontagne, Mickaël Rosa, Marie‐Chloé Boulanger, David Messika–Zeitoun, Marie-Annick A Clavel, Romain Capoulade, François Dagenais, Philippe Pîbarot, Patrick Mathieu, Yohan Bossé

Nature Communications · Mar 1, 2018Peer-reviewedGenomics