Molecular BiologybioRxivPreprint
A genetically encoded inhibitor of 53BP1 to stimulate homology-based gene editing
Marella D. Canny, Leo C.K. Wan, Amélie Fradet-Turcotte…·Daniel Durocher
This paper develops a genetically encoded inhibitor of 53BP1, i53, which enhances homology-based gene editing by blocking NHEJ and promoting HR in non-replicating cells.
DOI 10.1101/060954